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Fever with Non-pruritic Truncal Eruption

AZCOM/KRMC/Az Desert Dermatology
Kingman, Arizona

January, 2003

Presenters: Christian B. Anderson DO PharmD RPh, Tom Mackey DO

Program Director: Don A. Anderson DO


Clinical Presentation

4 Year Old Caucasian Male.

History

Chief Complaint: 4 yr old with unresponsive fever, irritability, adenopathy, orolabial erythema/fissures adenopathy, and distal edema.  Patient is a Caucasian male with 7day history of fever >102.5, malaise, anorexia, and irritability followed by a nonpruritic truncal eruption on day 2 then a progressively worsening conjunctival injection (mild), orolabial and nostril dryness and fissures, cervical adenopathy, and swollen/painful distal extremities. All of which proved to be unresponsive to acetaminophen, ibuprofen, amoxicillin, and azithromycin as variably dose by the patients
primary physician during the 7 days prior to referral to our clinic
 

Physical Examination

This 4 y.o. WDWN caucasian boy was alert yet unwilling to communicate (not his norm) and exhibited general lethargy, malaise, ease of irritability, and refusal to interact during the examination.

Physical exam as follows: Mild nonexudative conjunctival injection, severe orolabial/nasal mucosal erythema dryness and bleeding fissures, pharyngeal erythema with a white tonsillar exudate, brilliantly red tongue consistent with "strawberry tongue", bilateral cervical adenopathy ranging from 0.5 to 1.75cm, nonpruritic fine truncal erythematous maculopapular eruption sparing the distal extremities, and bilateral symmetric tense painful edema of his wrists, hands, ankles, and feet limiting his ability to ambulate and grasp objects. The remainder of the exam was considered within normal limits.

       
Figure 1 to Figure 5. (click image to zoom)   
 

Laboratory Tests

CMP, CBC with differential, UA all within normal limits with exception of mild leukocytosis.
 

Differential Diagnosis

What is your Diagnosis?

Viral exanthems

Bacterial diseases (scarlet fever, staphylococcal exfoliative syndromes, and leptospirosis)

Toxoplasmosis

Rickettsial disease (rocky mountain spotted fever),

Mucocutaneous Lymph Node Syndrome


American Osteopathic College of Dermatology, 2002