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Translucent and Hyperpigmented Papules and Nodules on the Upper Back and Neck

Western University College of Osteopathic Medicine of the Pacific,
Coast Dermatology
Torrance, CA

July, 2002

Presenters: Stephen G. Mallette, DO (Resident), Alpesh Desai, DO (Resident)

Program Director: David C. Horowitz, DO, FACD, Mark K. Horowitz, DO


Clinical Presentation

Patient: 54 years old  African American Female

History

Chief Complaint: Painless papules on the upper back for three months, which are increasing in size and number.

Signs and symptoms: The patient states that lesions are non-tender and have enlarged slowly over time. The patient also states that new lesions also occur over time. There is no pruritus or discharge from the lesions. They occur only on the upper back and neck.

Previous Treatment: Topical steroids, topical antibiotic and oral
antibiotics.

Other Information: The patient has been receiving dialysis since 1999 and has a fistula located on her left forearm. The patient moved to the United
States from Nigeria in 1997.


Physical Exam
 

Patient is a well-nourished African American female in no acute distress.
Multiple, hyperpigmented, waxy 2-mm to 4-mm dome shaped and flat topped papules located on the upper back and neck. Some of these lesions are arranged in parallel rows. There are also larger, thick, deeply pigmented nodules of irregular size and shapes on the back of the neck. These lesions were non-tender. There were no signs of infection. An AV fistula was noted on the left forearm. No other lesions were noted.


       
Figure 1 to Figure 4. (click image to zoom)

Laboratory Tests

PTH:                       1488.9 (10 - 65)
Calcium:                11 (8.5 - 11)
Total Protein:         8.4 (6.5 - 8)
Albumin                  8.2 (3 - 5)


Dermatohistopathology 

Microscopic description: Histology showed increased numbers of fibroblasts and increased mucin in the reticular dermis.
 

Differential Diagnosis

What is your Diagnosis?

Amyloidosis  

Lichen myxedematosus

Hypertrophic lichen planus

Nodular urticaria pigmentosa


American Osteopathic College of Dermatology, 2002