From YourSITE.com
Signs and Symptoms of Systemic Involvement in an Urticaria Pigmentosa Patient
By Andrea Costanza, DO, Nanda Channaiah, DO, Kevin Belasco, DO, Kevin Dehart, DO, Aaron Bruce, DO and Roger Sica, DO
Jan 30, 2007, 06:38
As noted in our patient, extensive workup has not revealed any evidence of systemic disease. Despite her relatively low mast cell burden, normal tryptase level, and negative bone marrow biopsy, she continues to have symptoms even with aggressive medical therapy. Our case supports the literature in that there is little correlation between clinical extent of disease and severity of symptoms.
This patient will be closely monitored in conjunction with an allergist, as there is a risk of progression into more aggressive disease. Repeat bone marrow biopsy should be considered if tryptase level trends upward.
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